Proteinuria selectivity index based upon α2-macroglobulin or IgM is superior to the IgG based index in differentiating glomerular diseases
نویسندگان
چکیده
منابع مشابه
High proteinuria selectivity index based upon IgM is a strong predictor of poor renal survival in glomerular diseases.
BACKGROUND The transport of large proteins across the glomerular capillary wall (GCW) may increase several fold in glomerular diseases. The occurrence of IgM in urine is a consequence of the presence of large defects or shunts in the GCW, whereas albuminuria is probably a result of an altered charge- and size-selectivity of the GCW. In order to examine whether patho-morphological differences in...
متن کاملGlomerular deposition of alpha 2-macroglobulin in glomerular diseases.
BACKGROUND alpha 2-macroglobulin (alpha 2M) is a glycoprotein involved in delivery of growth factors, regulation of matrix degrading enzymes and modulation of fibrinolysis factors, all of which are considered as important pathogenic mechanisms of glomerular injury. However, the role of alpha 2M in glomerular disease has not been extensively studied. The amount, frequency and local distribution ...
متن کاملC-Peptide-Based Index Is More Related to Incident Type 2 Diabetes in Non-Diabetic Subjects than Insulin-Based Index
BACKGROUND Diabetes can be efficiently prevented by life style modification and medical therapy. So, identification for high risk subjects for incident type 2 diabetes is important. The aim of this study is to identify the best β-cell function index to identify high risk subjects in non-diabetic Koreans. METHODS This is a retrospective longitudinal study. Total 140 non-diabetic subjects who u...
متن کاملMalmquist Productivity Index Based on Time Effect
In recent years, measuring and analyzing productivity changes is the main focus of variousresearches who study performance of organizations. All through widespread application ofMalmquist Productivity Index, different types of data should be considered thoroughly,otherwise any defective study of the related data and deciding factors may yield poor results.Practical Malmquist Productivity Index ...
متن کاملEntropy based Malmquist Productivity Index in Data Envelopment Analysis
Malmquist Productivity Index (MPI) is one of the most famous indices, which is used for estimating the productivity change of a Decision Making Unit (DMU) during the time. Virtually any empirical study that uses MPI, reports average of the productivity indices they estimate to represent the overall tendency in productivity changes. In such a case, productivity indices of a DMU are considered wi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Kidney International
سال: 1998
ISSN: 0085-2538
DOI: 10.1046/j.1523-1755.1998.00205.x